per conoscere, per riflettere, per costruire reti

Breaking — if true, this is massive news.

#OCEANIC-AF trial of oral Factor XI inhibitor vs Apixaban in pts w #afib being stopped early for inferiority. (We had just started randomizing recently)

@drjohnm | John Mandrola | 20.11.2023

cancer drugs with accelerated approval are less likely to receive high-level evidence ratings compared to those with regular approval. clarity in evidence level definitions can enhance clinicians, patients & payers.

@Oncoblogger | Raffaele Giusti | 20.11.2023

Am I alone in absolute desperation for new Paxlovid data?

@adamcifu | Adam Cifu | 20.11.2023

The country needs investment, public and private, not tax cuts.

@MichaelMarmot | Sir Michael Marmot | 19.11.2023

Distorsione cognitiva clamorosa che viviamo tutti sempre (oppure sono io pazzo/molto sfortunato): sul tabellone delle partenze della stazione l’ultimo binario a uscire è sempre quello del nostro treno.

@matteobordone | Matteo Bordone | 19.11.2023

It’s easy and popular to be cynical of a risky/bold project in a big company, and risky to be confident. This group-think that often favors (in resourcing and support) safe bets can be one of the greatest obstacles to making giant leaps in progress.

@scottbelsky | Scott Belsky | 19.11.2023

Responsibility for destroying Gaza’s health system—and killing thousands of Palestinian civilians—rests with Hamas and Israel’s government. Their leaders must be held accountable. Responding to the terror of Oct 7 and winning release of hostages did not justify another massacre.

@richardhorton1 | Richard Horton | 19.11.2023

una donna uccisa ogni tre giorni e non siamo nemmeno una repubblica islamica

@cicciorosina | Ciccio Rosina | 18.11.2023

In today’s hospitals, patients are being recast as clients, customers, or (worse) guests.

@theAtlantic | The Atlantic | 18.11.2023

As a child, I believed that the “Sabra and Shatila massacre” would be the most terrifying event I would ever remember.

However, with the passing years, each day has continued to prove me wrong.

@DrSusanNasif | Susan Nasif O-Adorisio | 18.11.2023

So many great projects ultimately fail because the people who started them allowed themselves to become subject to feckless and visionless corporate boards. Are there any good examples of how to actually build a board that is fit for purpose and helps to drive the mission?

@mbeisen | Michael Eisen | 18.11.2023

Be good, but don’t waste time proving it.

@DrTedros | Tedros Adhanom Ghebreyesus | 18.11.2023

The strain on scientific publishing. In 2022 the number of articles is 47% higher than in 2016. The amount of writing, reviewing and editing workload per scientist is increased enormously.

@Marc_Veld | Marc Veldhoen | 18.11.2023

forse ai figli non andrebbe insegnato solo l’ovvio rispetto per l’altro, ma anche per se stessi, la propria autonomia, la propria libertà. Insegnare che la vita non si esaurisce in una relazione. Maschi e femmine che siano

@PaolaDiCaro | Paola Di Caro | 18.11.2023

“People call [the antiscience movement] “misinfo” or “the infodemic” as though it’s just random junk out there on the Internet or social media, & it’s not—it’s organized, it’s well-financed, & it’s politically motivated.” -@PeterHotez

@tmprowell | Tatiana Prowell | 18.11.2023

A Top Science Journal @eLife Fired Its Editor Over a Pro-Palestinian Tweet: He Has No Regrets. @UCBerkeley ’s @mbeisen who is Jewish with relatives in Israel, isn’t one to back away from a fight.

@pash22 | Ash Paul | 18.11.2023

Ripassate, al limite.




@MauroBiani | Mauro Biani | 17.11.2023

“On average, low-income countries allocate more than twice as much money to servicing their debt as they do to social assistance, and 1.4 times more than to healthcare”: stark inequalities exposed by @MazzucatoM that must be addressed at #COP28.

@wtfrench76 | William French | 16.11.2023

If a favorite idea fails a well-designed test, it’s wrong.

@ProfFeynman | Prof. Feynman | 15.11.2023




@redpenblackpen | ex-X | 15.11.2023

Clarivate unveils the 2023 Highly Cited Researchers list—6,849 influential minds from 67 countries, with 83.8% emerging from the top 10 nations. The U.S. leads with 37.5% followed by China at 17.9%, doubling in 5 years.

@Clarivate | Clarivate | 15.11.2023

I wonder if the lack of progress on Alzheimer’s inspired the fraud or if a culture of fraud is the (or a) reason for a lack of progress

@conjurial | John Q Public | 14.11.2023

Lowering salt (one teaspoon) in the diet among middle-aged and older adults was as good an effect for reducing BP as a first-line anti-hypertensive drug, independent of severity of HTN or meds, in ~75% of people, from a randomized trial




@EricTopol | Eric Topol | 11.11.2023

anche oggi la guerra in Ucraina è finita, rimossa dall’informazione e dal dibattito. Un silenzio funzionale a non ammettere il fallimento dell’ormai conclusa controffensiva, il fallimento dell’opzione militare e il terremoto politico che, di conseguenza, si prepara

@_Nico_Piro | Nico Piro | 09.11.2023

Non credo di sbagliare, ma mi sembra che in un numero non trascurabile di soggetti che frequentano questa agorà la bandiera ucraina nel profilo sia l’indicatore del “doppio standard”: vittime per cui provare dolore vs vittime da ignorare (se non addirittura da biasimare).

@antonioclavenna | Antonio Clavenna | 07.11.2023

I won’t opt for a heart valve, chemotherapy or dialysis to extend my life. The goal shouldn’t be to live a long time. The goal is to live a meaningful life.

@ZekeEmanuel | Ezekiel Emanuel | 7.11.2023

Turns out news was not valuable to Facebook but its links are valuable to publishers, the opposite of what their lobbyists & pols contended. Note the regulatory capture: big publishers better off than small competitors.

@jeffjarvis | Jeff Jarvis | 7.11.2023

An editor resigns because of Elsevier’s failure to act on likely paper mill activity.

@RetractionWatch | Retraction Watch | 4.11.2023

Reading various COI statements. common theme I paraphrase ‘I do this consultancy/whatever but it never affects my judgement/conclusions’. anyone got an example of someone saying the opposite/or expressing uncertainty that maybe it does? (have yet to see one…)

@mgtmccartney | Margaret McCartney | 03.11.2023

ecently gave a talk to students about AI in health. One bit of advice I gave was even if you don’t implement these models in your daily work, you’ll encounter a lot of claims about them in future, so need to know how to usefully kick the tires…

@adamjkucharski | Adam Kucharski | 6.11.2023

I continue to think about the serious situation in Palestine and in Israel where many, many people have lost their lives. In God’s name, I beg you to stop: cease using weapons! I hope that avenues will be pursued so that an escalation of the conflict might be absolutely avoided.

@Pontifex | Pope Francis | 5.11.2023

Yes, we are compassionate.

We do not share your revolting ideology.

We are, by and large, altruists governed by psychopaths.

@GeorgeMonbiot | George Monbiot | 4.11.2023

Plan S “wants all versions of an article and its associated peer-review reports to be published openly from the outset, without authors paying any fees, and for authors, rather than publishers, to decide when and where to first publish their work.”

@Richard56 | Richard Smith | 1.11.2023